Vitamin D oral overdose.

Overdose of vitamin D is not common and often non-occurring, rather, lack of sufficient vitamin is more in occurrence. This is because the daily RDA according to the U.S. Dietary Reference intake tolerable upper intake level (UL) of vitamin D is 50 mcrograms for a male of 25 years old. This is often found less in vitamin supplements, let alone resulting in a overdose. Certain thampythical dosage, the stoss therapy has to do with vitamin D intake to over a thousand times the daily recommendation and vitamin D deficiency is still recorded.

The only resulting oral overdose, however is recorded due to mistakes in manufacturing process resulting in atherosclerosis and hypocalcaemia which can result in death. Apart form this kind of industrial accident, dosage of the vitamin D, orally is safe up to the done 50 microgram per day and researcher are of the opinion 10,000 IU is not even an overdose. Though, not yet discovered, but it is opinionated that certain chemical activities in the human body destroys excessive vitamin D and there is not continues increases of the blood levels of vitamins D thereby reducing the toxicity of the chemical but toxicity of level is rather very high in codliver oil if when overdosed mainly because of the high concentration of vitamin A contents.

However, other researcher are of the opinion that overdose of vitamin D is highly dangerous and can result in chromic diseases ischemic heart disease, hperclacurica and occurrence of bone loss there for intake of vitamin D supplement is dissuaded.

Vitamin E in cancer prevention and recovery
Research indicates that cancer patient who are exposed to enormous sunlight during treatment have a better chance of surviving the disease because of their exposure to sunlight lightens the presence of vitamin D While on the other hand treatment taken in the absence of enough sunlight lessen the chances of survival when compared to the former scenario. A report released in the American Journal by researchers indicates that vitamin D intake prevent occurence of colon cancer by 50% and breast cancer by 30% if daily intake of vitamin D is put at 25 micrograms.

But then according to expert on cancer, there is no static proof to that assertion. But this still holds a lot of controversy because other researcher groups at Stanford University known as the Feldman's group has shown how vitamin D, naproxen may serve as a therapy for prostate cancer.

In chromic disease
Such disease include 1h1 immune inflammation which occurs in rheumatism which can lead to abundant amount of macrophages converting 25D (i.e 25 hydroxy vitamin D) into 1,25D (i.e dihydro xyvitamin D hormonal form. This can result in vitamin D hypersensitivity which can result in symptoms such as hypercalcemia and hypervitaminosis D. 1,25D is highly active and the excessive conversion of it by macrophages may lead to serum vitamin D deficiency in diseases that are chronic.
In this case, supplementation with vitamin D will rather highten the level of 1.25 dihydroxyvitamin D which are able to result in dysfunction of alpha 2 thyroid and glucocorticoid receptors, thus having adverse effect on endocrine function and adaptive immune response.

The most recent research on vitamin D shows that it is also essential in fighting bacteria and viruses, such as the liny L. form bacteria. This bacteria is named after an institute called Lister because they were first discovered there in 1934.

L- forms are known to hide inside cells because they do not have their own cell wall. This disease is evident in diseases like systemic hupus erythematosus, sarcoidosis, rheumatoid arthritis to mention but a few.

Another research shows that 1.25D is displaced by enough 25D. This can hinder bacteria killing and innate immunity. If the disease is perpetuated by bacteria, and the reaction associated with bacterial killing is suppressed by vitamin D, it will lead to growth of the bacteria therefore causing more harm for so many years. With such suppression, it is no doubt the reason for the question of the vitamin D been a vitamin or not.

Another research (autoimmunity research foundation) supports the essentiality of the vitamin D dysregulation in many chromic diseases. The role of vitamin D and vitamin D receptor is also indicated be the efficacy of olmesartan, which serves or is known to block the receptor. This and other past research is a clear evidence that chronic diseases of various types are curbed and treated with vitamin D supplements.

The articles on this website should not be used as a basis for any form of diagnosis or treatment for any medical condition. Always seek professional medical advice.