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niacin.


The common sources of niacin, which is a product of amino acid (tryptophan) are fish, whole grain product, beans, yeast, meat and liver. Niacin is part of certain enzymes that reduce oxidation reactions, inhibits cholesterol creation and promote breakdown of triglyceride in lipid metabolism.

However, niacin when overdosed could result in various conditions like
1. dizziness,
2. faintness,
3. acute flushing,
4. liver dysfunction,
5. peptic ulcers,
6. high blood sugar,
7. irregular heart rhythms and gout.

On the other hand, when niacin is lacking in sufficient amount, it could result in pellagra. The common symptoms of pellagra include diarrhea, skin rashes and psychological disturbances.

You can prevent conditions resulting from over-dosage of niacin by staying away from diet or supplement that has high dosage of niacin.
Niacin has some side effects resulting from exessive intake.
This include:-
(1) Severe gastrointestinal problems
(2) Damage in the Liver

Here are symptoms that could come up due to excessive Niacin intake.
They include:-
(i) Paresthesias
(ii) Diabetes related symptoms
(iii) Diabetes
(iv) Flushing
(v) Tingling Skin

To get more insight on symptoms of high intake of niacin, literatures of associated conditions for Niacin overdose, underlying causes of Niacin overdose and the like, can easily be assessed.
Following a detailed finding relating to flush-free niacin on-line Medical, a conclusion has been drawn that flush - free niacimide does not have effect on reducing cholesterol. Rather inositol niacinamate salt of niacin performs this function. Unlike niacin that has several uncomfortable side effects, inositol does not have these effects.

Niacin in various forms.
One of the vital organs affected by niacin is the liver. So testing to ensure the liver is in proper shape is the right thing to do If niacin is excessively taken. The forms of niacin include:
(1) Niacinamide B3
(2) Time release niacin: This has a harder effect of the liver.
(3) Inositol Hexanicotinate

The time release niacin could do serious damage to the liver. Therefore you will need a regular check to test for the functioning of the liver if you use niacin in immediate release. However, if you are engaged in niacin therapy, ensure it is with the knowledge and okay of your doctor.

In the reduction of serum cholesterol levels, niacin is preferred because it is very cheap and very much available and it serves its purpose effectively. The total level and density of cholesterol is reduced with a consistent daily doses of 2 to 3 of niacin.
(1) Triglyceride level is reduced by 35% to 55%
(2) It also reduces lipoprotein
(3) Lipoprotein cholesterol (LDL-C) by an average of 20% to 30%
(4) Increases high - density lipoprotein cholesterol (HDL-C) 20% to 35%

Niacin, in terms of prevention, reduces mortality from coronary artery disease and prevents bite acid resin secondarily. It also has effect on the atherosclerosis by slowing its progression. 10 day supply of this is not more than $2.00. However, research by Mckenny et al (Medical College of Virginia School of Pharmacy) show that niacin therapy could be dangerous.

The articles on this website should not be used as a basis for any form of diagnosis or treatment for any medical condition. Always seek professional medical advice.

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